Principles of Inheritance and Variation

Chromosome theory of inheritance


  • Sutton and Boveri, proposed the theory which was later confirmed by T.H. Morgan.
  • The theory explains that the genes are present at a specific loci on chromosomes.
  • Later the chromosomes segregate and assort independently during meiosis and further recombine during fertilization.
  • Gametes constitute a bridge between 2 generations, that must carry all hereditary traits.
  • Both sperm and egg equally contribute in the heredity of offspring and there is a fusion between egg and sperm nuclei.
  • Chromosomes are located in nucleus and therefore they must carry the hereditary traits.
  • In many organisms, sex of an individual is determined by sex chromosomes.

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