Hardy - Weinberg's principle

  • It describes the stability of population and species over a number of generations and is applicable under following conditions
    ⇒ No mutation ⇒ No gene flow ⇒ No genetic drift ⇒ No genetic recombination ⇒ No natural selection pressure
  • According to HWE, gene frequencies will remain constant if all above factors are satisfied.
  • Let p, q etc., be the individual frequencies of allele A and a respectively frequency of AA individuals ⇒ p2 ; frequency of aa ⇒ q2 and Aa = 2 pq.
  • Therefore, p2 + 2pq + q2 = 1; (p + q = 1)
    where p = dominant allele frequency
              q = recessive allele frequency
             p2 = homozygous dominant genotype
          2 pq = heterozygous genotype
             q2 = homozygous recessive genotype
  • Evolution proceeds when genetic equilibrium is upset.

Watch this video for the topic from 24:11 to 34:55

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